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  3. Medical: Pharmaceuticals

exhibit an AUC ratio of 5-fold or more

Russian translation: препараты, для которых отношение AUC (AUCi/AUC) составляет 5 и более

21:16 Jan 21, 2018
English to Russian translations [PRO]
Medical - Medical: Pharmaceuticals
English term or phrase: exhibit an AUC ratio of 5-fold or more
Sensitive substrates:
Drugs that exhibit an AUC ratio (AUCi/AUC) of 5-fold or more when coadministered with a known potent inhibitor, where AUCi is the AUC of the substrate when coadministered with a known potent inhibitor and AUC is the AUC of substrate alone.
Substrates with narrow therapeutic index:
Drugs whose exposure-response indicates that increases in their exposure levels by the concomitant use of potent inhibitors may lead to serious safety concerns (eg, Torsade de Pointes).
Anastasia Serdyukova
Russian Federation
Local time: 05:07
Russian translation:препараты, для которых отношение AUC (AUCi/AUC) составляет 5 и более
Explanation:
*
Selected response from:

Natalie
Poland
Local time: 04:07
Grading comment
4 KudoZ points were awarded for this answer



Summary of answers provided
4препараты, для которых отношение AUC (AUCi/AUC) составляет 5 и более
Natalie


  

Answers


12 mins   confidence: Answerer confidence 4/5Answerer confidence 4/5
exhibit an auc ratio of 5-fold or more
препараты, для которых отношение AUC (AUCi/AUC) составляет 5 и более


Explanation:
*

Natalie
Poland
Local time: 04:07
Specializes in field
Native speaker of: Russian
PRO pts in category: 13399
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