Sep 3, 2022 06:22
2 yrs ago
34 viewers *
angol term
laddering
angol - magyar
Orvosi
Orvosi: Gyógyszerek
Treatment for SM patients
Stimuli:
Problem statement 1
Getting my patients with mild MS to commit to first-line treatment is important, but I worry that they won’t be able to commit because of frequent dosing and tolerability issues.
Stimuli:
Laddering 1
Key attributes
This product has an established profile of efficacy and safety with the convenience of once-weekly dosing
----
The text has an indentation after the term "Laddering 1" and several points are listed, first one is "Key attributes" and each point has further indentation and description.
Problem statement 1
Getting my patients with mild MS to commit to first-line treatment is important, but I worry that they won’t be able to commit because of frequent dosing and tolerability issues.
Stimuli:
Laddering 1
Key attributes
This product has an established profile of efficacy and safety with the convenience of once-weekly dosing
----
The text has an indentation after the term "Laddering 1" and several points are listed, first one is "Key attributes" and each point has further indentation and description.
Proposed translations
(magyar)
| 5 | kérdések réteges alkalmazása |
JANOS SAMU
|
Proposed translations
1 óra
JANOS SAMU
Egyesült Államok
Egyesült Államok
Works in field
Egyesült Államok
We know the language and the system too.
Works in: angol - zzz egyéb zzz, angol - lao, angol - litván, and 91 more.
Related KudoZ points
:
100
kérdések réteges alkalmazása
A lényeg az, hogy a kérdések alkalmazásánál olyan kérdéseket kell feltenni, amelyekkel egy-egy kis információréteget tudunk a rejtett lényegről lehámozni és fokozatosan jutunk el célinformációhoz.
A ladder is a tool designed to allow you to reach something otherwise unreachable. In the same way, “laddering” as applied to structured questioning is a technique designed to acquire nuggets of information which are otherwise very difficult to get at.
The method is performed by using probes. Probing means to “peel back the layers” of the informant’s experience.
A ladder is a tool designed to allow you to reach something otherwise unreachable. In the same way, “laddering” as applied to structured questioning is a technique designed to acquire nuggets of information which are otherwise very difficult to get at.
The method is performed by using probes. Probing means to “peel back the layers” of the informant’s experience.
Reference:
https://www.b2binternational.com/publications/laddering-technique-find-what-people-value/
Peer comment(s):
| neutral |
liz askew
: how does this relate to MS?
7 óra
|
|
Conclusively, the major symptom is SM (https://how-emotions-are-made.com/notes/Patient_SM) and the patient also had a mild MS, which happens with many admissions. So, the primary issue (fear) must be handled differently, first psychologically.
|
Reference comments
8 óra
Reference:
comment
I am concerned because I cannot find "laddering" on any site regarding MS (multiple sclerosis), only "ladder" in term sof "analgesic ladder", see:
Management of pain in advanced disease - Oxford Academic
https://academic.oup.com › bmb › article-pdf › ldu010
by DG Harris · 2014 · Cited by 36 — Key words: analgesic ladder, cancer, heart failure, liver failure, palliative, pain, motor neurone disease, multiple sclerosis, renal ...
--------------------------------------------------
Note added at 8 hrs (2022-09-03 15:02:25 GMT)
--------------------------------------------------
https://professionals.wrha.mb.ca/old/professionals/files/PDT...
By the ladder:
If pain occurs there should be prompt administration of drugs
in the following order:
• non-opiods (e. g. acetaminophen)
• as necessary, mild opiods (e. g. codeine)
• then strong opiods (e. g. morphine or
hydromorphone) until the patient is free of pain.
Drug selection should be appropriate to the severity of the pain. It may be most appropriate with severe pain to
begin at the top of the ladder with a strong opioid; it is not always
necessary to start at step one. When pain is controlled, the patient should be maintained on the dose that is
effective. It is usually not necessary to step down the ladder unless the cause of pain is believed to have resolved
(e.g. post-operatively, in remission from cancer).
Along any step in the ladder, additional drugs – “adjuvants”- may be used. Adjuvants include: antidepressants
(e.g. amitriptyline), anticonvulsants (e.g. gabapentin), corticosteroids (e. g. dexamethasone), and anxiolytics
(e.g. diazepam)
--------------------------------------------------
Note added at 1 day 10 hrs (2022-09-04 17:21:28 GMT)
--------------------------------------------------
https://www.gosh.nhs.uk/conditions-and-treatments/medicines-...
Multiple sclerosis disease-modifying drugs: first line treatments
Disease-modifying drugs (DMDs) work by interacting with the immune system and calming the inflammation that is attacking the central nervous system.
There are currently five DMDs used as first line treatments for relapsing-remitting multiple sclerosis.
Beta interferon 1a (available under the trade name Avonex®) – given by injection into a muscle (intramuscular) once a week using a pre-filled syringe.
Beta interferon 1a (Rebif®) – given by injection under the skin (subcutaneously) three times a week using a pre-filled syringe.
Beta interferon 1b (Betaferon® and Extavia®) – given by injection under the skin (subcutaneously) every other day. The injection needs to be prepared by mixing the ingredients before drawing it up in a syringe.
Glatiramer acetate (Copaxone®) – given by injection under the skin (subcutaneously) once a day using a pre-filled syringe.
There are two drugs used for second line treatment (fingolimod and natalizumab) covered in another information sheet.
The treatments do not cure MS, but can reduce the number of relapses. In adult trials, the relapses decreased by around a third and the effect on relapses in young people with MS appears to be significantly greater than this. By decreasing the number of relapses, it appears that the long-term development of disability can also be slowed down. Some research also suggests that the earlier treatment starts, the more effective it is likely to be. These drugs may also not work for everyone, and the pros and cons of treatment need to be constantly reviewed.
--------------------------------------------------
Note added at 1 day 11 hrs (2022-09-04 17:22:46 GMT)
--------------------------------------------------
another instance of "ladder";
Multiple sclerosis, a treatable disease - PMC - NCBI
https://www.ncbi.nlm.nih.gov › articles › PMC6297710
by A Doshi · 2017 · Cited by 186 — Escalation – starting with a less efficacious, but potentially safer, therapy and then moving up the treatment ladder if there is treatment failure. Clinical ...
so it could be referring to "treatment ladder" too
Management of pain in advanced disease - Oxford Academic
https://academic.oup.com › bmb › article-pdf › ldu010
by DG Harris · 2014 · Cited by 36 — Key words: analgesic ladder, cancer, heart failure, liver failure, palliative, pain, motor neurone disease, multiple sclerosis, renal ...
--------------------------------------------------
Note added at 8 hrs (2022-09-03 15:02:25 GMT)
--------------------------------------------------
https://professionals.wrha.mb.ca/old/professionals/files/PDT...
By the ladder:
If pain occurs there should be prompt administration of drugs
in the following order:
• non-opiods (e. g. acetaminophen)
• as necessary, mild opiods (e. g. codeine)
• then strong opiods (e. g. morphine or
hydromorphone) until the patient is free of pain.
Drug selection should be appropriate to the severity of the pain. It may be most appropriate with severe pain to
begin at the top of the ladder with a strong opioid; it is not always
necessary to start at step one. When pain is controlled, the patient should be maintained on the dose that is
effective. It is usually not necessary to step down the ladder unless the cause of pain is believed to have resolved
(e.g. post-operatively, in remission from cancer).
Along any step in the ladder, additional drugs – “adjuvants”- may be used. Adjuvants include: antidepressants
(e.g. amitriptyline), anticonvulsants (e.g. gabapentin), corticosteroids (e. g. dexamethasone), and anxiolytics
(e.g. diazepam)
--------------------------------------------------
Note added at 1 day 10 hrs (2022-09-04 17:21:28 GMT)
--------------------------------------------------
https://www.gosh.nhs.uk/conditions-and-treatments/medicines-...
Multiple sclerosis disease-modifying drugs: first line treatments
Disease-modifying drugs (DMDs) work by interacting with the immune system and calming the inflammation that is attacking the central nervous system.
There are currently five DMDs used as first line treatments for relapsing-remitting multiple sclerosis.
Beta interferon 1a (available under the trade name Avonex®) – given by injection into a muscle (intramuscular) once a week using a pre-filled syringe.
Beta interferon 1a (Rebif®) – given by injection under the skin (subcutaneously) three times a week using a pre-filled syringe.
Beta interferon 1b (Betaferon® and Extavia®) – given by injection under the skin (subcutaneously) every other day. The injection needs to be prepared by mixing the ingredients before drawing it up in a syringe.
Glatiramer acetate (Copaxone®) – given by injection under the skin (subcutaneously) once a day using a pre-filled syringe.
There are two drugs used for second line treatment (fingolimod and natalizumab) covered in another information sheet.
The treatments do not cure MS, but can reduce the number of relapses. In adult trials, the relapses decreased by around a third and the effect on relapses in young people with MS appears to be significantly greater than this. By decreasing the number of relapses, it appears that the long-term development of disability can also be slowed down. Some research also suggests that the earlier treatment starts, the more effective it is likely to be. These drugs may also not work for everyone, and the pros and cons of treatment need to be constantly reviewed.
--------------------------------------------------
Note added at 1 day 11 hrs (2022-09-04 17:22:46 GMT)
--------------------------------------------------
another instance of "ladder";
Multiple sclerosis, a treatable disease - PMC - NCBI
https://www.ncbi.nlm.nih.gov › articles › PMC6297710
by A Doshi · 2017 · Cited by 186 — Escalation – starting with a less efficacious, but potentially safer, therapy and then moving up the treatment ladder if there is treatment failure. Clinical ...
so it could be referring to "treatment ladder" too
Peer comments on this reference comment:
| agree |
JANOS SAMU
: S.M. (patient) S.M., is an American woman with a peculiar type of brain damage that prevents her from experiencing fear. First described by scientists in 1994, [1] she has had exclusive and complete bilateral amygdala
1 óra
|
|
but "mild MS" in the text, = mild multiple sclerosis?
|
Discussion