This question was closed without grading. Reason: Other
Aug 11, 2023 11:33
9 mos ago
45 viewers *
English term

ATM

English to Spanish Medical Medical (general)
thrombocytopenia sec to chronic alcoholic liver disease (D69.6 - Thrombocytopenia,
unspecified, HCC:48, K70.9 - Alcoholic liver disease, unspecified, HCC:28) [Med Pblm] IDT PlT
Ct: 177 WNL (3/6/2023). ATM. 1/22/2023 : PT count N as per CBC on 11/3/22. No reported bleeding

This text is a medical record, filled with abbreviations... I asked the client about this and they say they don't know :(. Any ideas? I've been researching a lot but nothing makes complete sense...

If nothing fits, should I just leave it as it is, maybe with a note? I've been translating for more than 20 years and never came up with a situation when the clien't can't provide an explanation...

Thanks!
References
ATM

Proposed translations

3 mins

ATM

Declined
Déjalo en inglés:

https://iate.europa.eu/search/result/1691739677009/1

ATM gene = gen ATM
Peer comment(s):

neutral Neil Ashby : "ATM gene" followed by a date. What does that mean in a medical report?
1 hr
Neil. This is an example. You probably didn't follow the link I provided to IATE.
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+1
4 hrs

Microangiopatía trombótica aguda (MAT)

Declined
Thrombocytopenia can be secondary to chronic or acute liver diseases.

https://dx.doi.org/10.1016/j.nefro.2015.03.003: In a case report, a diagnosis of acute thrombotic microangiopathy (ATM) was made in a patient with subcapsular liver hematoma, which was thought to be a consequence of hepatic blood flow obstruction due to fibrin deposits within hepatic sinusoids, resulting in periportal necrosis and intrahepatic hemorrhage. Likewise, the authors believed that vascular rupture might result from hepatic blood flow obstruction secondary to complement-induced microvascular thrombosis.
Peer comment(s):

agree Alicia Tapias Soler
24 days
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Reference comments

1 hr
Reference:

ATM

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7080576/

To overcome the rising burdens of nonalcoholic fatty liver disease, mechanistic linkages in mitochondrial dysfunction, inflammation and hepatic injury are critical. As ataxia telangiectasia mutated (ATM) gene oversees DNA integrity and mitochondrial homeostasis, we analyzed mRNAs and total proteins or phosphoproteins by arrays in subjects with healthy liver, fatty liver or nonalcoholic steatohepatitis. F

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Note added at 1 heure (2023-08-11 13:08:53 GMT)
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wiki:

ATM serine/threonine kinase or Ataxia-telangiectasia mutated, symbol ATM, is a serine/threonine protein kinase that is recruited and activated by DNA double-strand breaks. It phosphorylates several key proteins that initiate activation of the DNA damage checkpoint, leading to cell cycle arrest, DNA repair or apoptosis. Several of these targets, including p53, CHK2, BRCA1, NBS1 and H2AX are tumor suppressors.
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